Matthieu Louis

Sensorimotor computations underlying larval chemotaxis

A wide range of organisms follow chemical cues to locate food sources. Behavioral strategies employed for chemotaxis have been studied across phyla, but the neural computations underlying odor-guided navigation remain poorly understood. We use a combination of electrophysiology, optogenetics, quantitative behavior and computational modeling to understand how dynamical olfactory signals experienced during chemotaxis are processed by the first-order sensory neurons of the Drosophila larva and how this information is converted into navigational decisions. Our work aims to clarify the link between neural computation at the sensory periphery and decision-making processes that direct navigation in sensory landscapes.
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