Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge UK
The set of biochemical reactions by which an E. coli bacterium detects and responds to distant sources of attractant or repellent molecules is probably the simplest and best-understood example of a cell-signalling pathway. Bray’s lab, at the Department of Physiology, Development and Neuroscience (PDN) of the University of Cambridge, focuses on Systems and Computational Neuroscience. They are developing detailed computer simulations, tied to experimental data, to assess current views of how this pathway works and identify areas of ignorance. In 2006 Bray received the Microsoft European Science Award.