Isalan´s talk highlights
Due to confidentiality issues we cannot include a summary of Mark Isalan´s talk. Find the abstract published in the Conference Book below:
In this talk, we will focus on synthetic gene regulatory networks in bacteria, with work done in collaboration with the Sharpe Group (CRG). We developed a network scaffold to engineer a complete family of related but distinct topologies, rather than individual networks on a case-by-case basis. The system allows us to explore a unified design space around a set of minimal stripe forming networks. We could thus build computationally-predicted mechanisms, some of them not yet found in nature. Furthermore, we validated the mechanisms of our networks by mutations that resulted in phenotypes as predicted by our computational model.